TB-500
Thymosin Beta-4 fragment studied for wound healing and cell migration
Also known as: Thymosin Beta-4, Tβ4, TB4
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A synthetic analogue of the actin-sequestering domain of Thymosin Beta-4 (residues 17–23, LKKTETQ), studied for its role in G-actin sequestration, regulation of actin polymerisation dynamics, lamellipodia formation, and cell motility in in vitro wound healing assays. Investigated as a research tool in cytoskeletal biology and connective tissue repair models.
Properties
| Appearance | White to off-white lyophilized powder |
|---|---|
| Cas Number | 80714-61-0 |
| Form | Lyophilized powder |
| Heavy Metals | None Detected |
| Molecular Formula | C6H10N2O3 |
| Molecular Weight | ~813.9 g/mol |
| Pubchem Cid | PubChem CID: 16133836 ↗ |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in water (≥5 mg/mL). |
| Storage | Store at -20°C. |
Available Batches
| Lot | Expiry | Certificate of Analysis |
|---|---|---|
| T2505 | n/a |
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Frequently Asked Questions
TB-500 is a synthetic fragment of Thymosin Beta-4, the active 43-amino-acid region responsible for cell migration and differentiation. It promotes actin polymerisation, cell migration, and angiogenesis in preclinical tissue repair models.