Semax
ACTH(4-7) proline-extended heptapeptide studied for BDNF upregulation
Also known as: ACTH 4-7 Pro-Gly-Pro
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An ACTH(4-7) proline-extended heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) studied for its capacity to upregulate BDNF and NGF expression, bind melanocortin receptors (MC4R), and exhibit neuroprotective properties in ischaemic and hypoxic preclinical research models. Used as a research tool in neurotrophin signalling studies.
Properties
| Appearance | White to off-white lyophilized powder |
|---|---|
| Cas Number | 80714-61-0 |
| Form | Lyophilized powder |
| Heavy Metals | None Detected |
| Molecular Formula | C37H51N9O10S |
| Molecular Weight | ~813.9 g/mol |
| Pubchem Cid | PubChem CID: 80714-61-0 ↗ |
| Purity | ≥99% (HPLC) |
| Solubility | Soluble in water (≥20 mg/mL). |
| Storage | Store at -20°C. |
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Frequently Asked Questions
Semax is a synthetic analogue of adrenocorticotropic hormone (ACTH) fragment ACTH(4-10). It is a neuropeptide studied for neuroprotective, nootropic, and immunomodulatory properties. Research explores its effects on BDNF expression, synaptic plasticity, and neuroinflammation.